Used Medium Duty Isuzu Trucks For Sale

Your Current Search
Industry
Trucks
Manufacturer
Isuzu
GVWR Category
Medium Duty
Condition
Used
Click the to remove the filter.
Narrow Your Search
Keyword Search
Search within the selected criteria
Equipment Type
Trucks (735)
Make
Isuzu (735)
Model
Select a category to view available models.
Condition
Used (735)
Model Year
-
GVWR Category
Medium Duty (735)
Transmission Type
Transmission Speed
Drive Train
4x2 (97)
Suspension Type
Cab Style
Fuel Type
Mileage
-
Horsepower
-
Price
-
Country
State / Region
Select a country to view available states.
Market Type

Showing 1 - 25 of 735 Listings

1 - 25 of 735 listings
1 - 25 of 735 listings
Featured Item
2012 Isuzu NPR Box Truck, Moving, Hauler, City Truck, Dock Height, Clean, Ready to go, Delivery

2012 Isuzu NPR Box Truck, Moving, Hauler, City Truck, Dock Height, Clean, Ready to go, Delivery

Recently Updated
$19,999 USD
TUESDAY DEALS, PRESIDENTS DAY DEALS ARE STILL HERE, CALL US 410-620-9800 ASK FOR ROSE, 929 W PULASKI HWY ELKTON MD 21921 ,
ConditionUsed
Duty ClassMedium Duty Box Truck
Engine ModelL96
Drivetrain4x2
Rear AxleTandem Axle
Stock Number804853
MLS Number13524510
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Elkton, MD, US
Sold By
Complete Recycling Group LLC
Featured Item
Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2019 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

Recently Updated
$40,071 USD
ConditionUsed
Usage34,702 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.77 ratio
Door TypeRoll up
LiftgateYes
Stock Number838128
MLS Number14054304
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Bolingbrook, IL, US
Sold By
Ryder
Featured Item
Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2019 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

Recently Updated
$35,919 USD
ConditionUsed
Usage108,294 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number233845
MLS Number13998371
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Fontana, CA, US
Sold By
Ryder
Featured Item
Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2019 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$31,997 USD
ConditionUsed
Usage144,713 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number810474
MLS Number14107631
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Syracuse, NY, US
Sold By
Ryder
Featured Item
Isuzu NRR 6 ft Box Truck - Automatic

2020 Isuzu NRR 6 ft Box Truck - Automatic

$26,900 USD
16' MORGAN BOX, 86" Door Opening, Palfinger LIFTGATE, Automatic Transmission..
ConditionUsed
Usage153,052 Miles
Duty ClassMedium Duty Box Truck
Box Length6 ft.
Drivetrain4x2
TransmissionAutomatic
Rear AxleSingle Axle
Stock Number8273T
MLS Number14004858
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/29/2026
Location
Shrewsbury, NJ, US
Sold By
Schwartz Truck Center
Featured Item
Isuzu NPR HD 14 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2019 Isuzu NPR HD 14 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$33,862 USD
ConditionUsed
Usage133,411 Miles
Duty ClassMedium Duty Box Truck
Box Length14 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number233451
MLS Number14080740
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/16/2026
Location
Salisbury, MA, US
Sold By
Ryder
Featured Item
Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2018 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$28,957 USD
ConditionUsed
Usage144,956 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number761931
MLS Number14076736
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Farmingdale, NY, US
Sold By
Ryder
Featured Item
Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2018 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$34,833 USD
ConditionUsed
Usage88,102 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.77 ratio
Door TypeRoll up
LiftgateYes
Stock Number825007
MLS Number14052665
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Kearny, NJ, US
Sold By
Ryder
Featured Item
Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door

2019 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door

$35,130 USD
ConditionUsed
Usage119,577 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
Stock Number242280
MLS Number14047987
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/16/2026
Location
Springfield, MA, US
Sold By
Ryder
Featured Item
Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2020 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$29,145 USD
ConditionUsed
Usage179,315 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number245062
MLS Number14044652
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Allentown, PA, US
Sold By
Ryder
Featured Item
Isuzu NQR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

2019 Isuzu NQR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

Price Drop $53,587 USD
ConditionUsed
Usage91,615 Miles
Duty ClassMedium Duty Refrigerated Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End5.12 ratio
Door TypeRoll up
LiftgateYes
Stock Number899247
MLS Number14043117
CategoryRefrigerated Trucks
Last Updated2/14/2026
Location
Salisbury, MA, US
Sold By
Ryder
Featured Item
Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2017 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

Price Drop $31,630 USD
ConditionUsed
Usage98,137 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number685147
MLS Number14020817
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Beltsville, MD, US
Sold By
Ryder
2020 Isuzu NRR, 16' Refrigerated Box, Carrier Supra 860 W/Low Hours, Electric Standby.

2020 Isuzu NRR, 16' Refrigerated Box, Carrier Supra 860 W/Low Hours, Electric Standby.

Recently Updated
$32,995 USD
FOR SALE: 2020 ISUZU NRR 16' REFRIGERATED BOX TRUCK WITH LIFTGATE, For sale is a 2020 Isuzu NRR configured with a 16-foot insulated refrigerated box and tuck-under liftgate, ideal for...
ConditionUsed
Usage6,939 Hours
Duty ClassMedium Duty Refrigerated Truck
Upfit TypeRefrigerated Box Van
Upfit MakeSupreme
Upfit ModelVGPEN16091096
Box Length16 ft.
Horse Power210 HP
Engine ModelIsuzu 4HK1-TC
Drivetrain4x2
Transmission6 Speed Automatic
Reefer UnitCarrier Supra 860
SuspensionSpring
Rear AxleSingle Axle
Rear End18,660 lb
Door TypeRoll up
Roof TypeTranslucent
LiftgateYes
Stock Number300341
MLS Number14129847
CategoryRefrigerated Trucks
Last Updated2/17/2026
Location
Miami, FL, US
Sold By
Truck and Van Outlet
Isuzu FTR Box Truck - 260HP, 6 Speed Automatic, Roll up Door

2023 Isuzu FTR Box Truck - 260HP, 6 Speed Automatic, Roll up Door

Recently Updated
$78,750 USD
Used 2023 Isuzu FTR Box Truck with 260HP Cummins B6.7 diesel engine, 6-speed Allison automatic transmission, 224" wheelbase, air ride suspension, 100-gallon fuel capacity, and roll-up door....
ConditionUsed
Usage122,090 Miles
Duty ClassMedium Duty Box Truck
Horse Power260 HP
Engine ModelCummins B6.7
Transmission6 Speed Automatic
SuspensionAir Ride
Rear AxleSingle Axle
Rear End19,000 lb 6.14 ratio
Door TypeRoll up
Stock Number224764
MLS Number14062755
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Greensboro, NC, US
Sold By
Penske Used Trucks
Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

2022 Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Newly Listed
Contact for price
Used 2022 Isuzu NPR XD box truck for sale, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, 30-gallon fuel capacity, single rear axle, spring suspension, 144\" height...
ConditionUsed
Usage89,471 Miles
Duty ClassMedium Duty Box Truck
Horse Power215 HP
Engine ModelIsuzu 4HK1TC
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End14,550 lb 4.78 ratio
Door TypeRoll up
Stock Number466665
MLS Number14147473
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Pasco, WA, US
Sold By
Penske Used Trucks
Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

2022 Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Newly Listed
Contact for price
Used 2022 Isuzu NPR XD Box Truck for sale, 42,852 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, 144" height, 150" wheelbase, roll-up door. Check it out.
ConditionUsed
Usage42,852 Miles
Duty ClassMedium Duty Box Truck
Horse Power215 HP
Engine ModelIsuzu 4HK1TC
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End14,550 lb 4.78 ratio
Door TypeRoll up
Stock Number466663
MLS Number14147472
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Spokane Valley, WA, US
Sold By
Penske Used Trucks
Isuzu NRR Refrigerated Truck - 215HP, 6 Speed Automatic, Thermo King T690

2022 Isuzu NRR Refrigerated Truck - 215HP, 6 Speed Automatic, Thermo King T690

Recently Updated
$76,250 USD
Used 2022 Isuzu NRR Refrigerated Truck for sale, 39,810 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, single rear axle, 15,550 lbs rear axle capacity. Check...
ConditionUsed
Usage42,144 Miles
Duty ClassMedium Duty Refrigerated Truck
Horse Power215 HP
Engine ModelIsuzu 4HK1TC
Transmission6 Speed Automatic
Reefer UnitThermo King T690
SuspensionSpring
Rear AxleSingle Axle
Rear End14,550 lb 5.57 ratio
Door TypeRoll up
Stock Number465418
MLS Number14105606
CategoryRefrigerated Trucks
Last Updated2/17/2026
Location
Anaheim, CA, US
Sold By
Penske Used Trucks
Isuzu NQR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NQR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Newly Listed
$51,250 USD
Used 2021 Isuzu NQR Box Truck for sale, 57,721 miles, 215 HP diesel engine, 6-speed Aisin automatic transmission, 200" wheelbase, roll-up door, black color, medium duty GVWR. Check it out!
ConditionUsed
Usage57,721 Miles
Duty ClassMedium Duty Box Truck
Horse Power215 HP
Engine ModelIsuzu 4HK1TC
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End12,980 lb 5.12 ratio
Door TypeRoll up
Stock Number378636
MLS Number14147296
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Brook Park, OH, US
Sold By
Penske Used Trucks
Isuzu NQR Refrigerated Truck - 215HP, Automatic, Thermo King, Liftgate

2016 Isuzu NQR Refrigerated Truck - 215HP, Automatic, Thermo King, Liftgate

Recently Updated
$9,900 USD
2016 Isuzu NQR Reefer, Thermo King Engine Drive Reefer, 18'x102" box, 2 rows of E-Track, 1600# Rear Rail Gate. Truck has been fleet maintained from day one and is ready to get back to work!!...
ConditionUsed
Usage221,172 Miles
Duty ClassMedium Duty Refrigerated Truck
Horse Power215 HP
Drivetrain4x2
TransmissionAutomatic
Reefer UnitThermo King
Rear AxleSingle Axle
Rear End12,980 lb
Door TypeRoll up
LiftgateYes
Stock Number8206
MLS Number13720997
CategoryRefrigerated Trucks
Last Updated2/17/2026
Location
Latrobe, PA, US
Sold By
Fox & James, Inc.
Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2019 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

Newly Listed
$39,705 USD
ConditionUsed
Usage97,074 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number874177
MLS Number14145565
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/15/2026
Location
Beltsville, MD, US
Sold By
Ryder
Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

2020 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

Recently Updated
$38,995 USD
ConditionUsed
Usage90,554 Miles
Duty ClassMedium Duty Box Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Door TypeRoll up
LiftgateYes
Stock Number273044
MLS Number13754129
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/15/2026
Location
Farmingdale, NY, US
Sold By
Ryder
Isuzu NPR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic

2018 Isuzu NPR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic

Newly Listed
$47,033 USD
ConditionUsed
Usage171,384 Miles
Duty ClassMedium Duty Refrigerated Truck
Box Length16 ft.
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.77 ratio
Door TypeRoll up
Stock Number809939
MLS Number14145544
CategoryRefrigerated Trucks
Last Updated2/15/2026
Location
Oklahoma City, OK, US
Sold By
Ryder
Isuzu NPR Box Truck - 215HP, 6 Speed Automatic

2016 Isuzu NPR Box Truck - 215HP, 6 Speed Automatic

Newly Listed
$19,929 USD
ConditionUsed
Usage163,307 Miles
Duty ClassMedium Duty Box Truck
Horse Power215 HP
Engine Model4HK1TC'10 215/2500
Transmission6 Speed Automatic
SuspensionLeaf Springs
Rear AxleSingle Axle
Rear End4.55 ratio
Stock Number654740
MLS Number14145524
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/15/2026
Location
Beltsville, MD, US
Sold By
Ryder
Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

2022 Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Newly Listed
$57,250 USD
Used 2022 Isuzu NPR XD Box Truck for sale, 34,999 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, single rear axle, 15' wheelbase, 30 gal fuel capacity,...
ConditionUsed
Usage34,999 Miles
Duty ClassMedium Duty Box Truck
Horse Power215 HP
Engine ModelIsuzu 4HK1TC
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End14,550 lb 4.78 ratio
Door TypeRoll up
Stock Number466664
MLS Number14144865
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Lakewood, WA, US
Sold By
Penske Used Trucks
Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

2022 Isuzu NPR XD Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Newly Listed
$56,000 USD
Used 2022 Isuzu NPR XD Box Truck for sale, 43,980 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, single rear axle, spring suspension, 144" height. Check it...
ConditionUsed
Usage43,980 Miles
Duty ClassMedium Duty Box Truck
Horse Power215 HP
Engine ModelIsuzu 4HK1TC
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End14,550 lb 4.78 ratio
Door TypeRoll up
Stock Number466662
MLS Number14144849
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated2/17/2026
Location
Lakewood, WA, US
Sold By
Penske Used Trucks
Did you find what you were looking for? Yes No