Isuzu NPR Trucks For Sale

Featured Item

2020 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door

$19,000 USD

Condition	Used
Usage	242,354 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.55 ratio
Door Type	Roll up
Stock Number	271871
MLS Number	14423023
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/6/2026
Location	Ashland, VA, US
Sold By	Ryder

Featured Item

2019 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$28,990 USD

Condition	Used
Usage	162,942 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.55 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	264919
MLS Number	14399766
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/6/2026
Location	Pittsburgh, PA, US
Sold By	Ryder

Featured Item

2018 Isuzu NPR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

$43,712 USD

Condition	Used
Usage	193,217 Miles
Duty Class	Medium Duty Refrigerated Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	812599
MLS Number	14398039
Category	Refrigerated Trucks
Last Updated	7/6/2026
Location	Greensboro, NC, US
Sold By	Ryder

Featured Item

2017 Isuzu NPR 18 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

Price Drop $46,014 USD

Condition	Used
Usage	66,215 Miles
Duty Class	Medium Duty Refrigerated Truck
Box Length	18 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Swing
Liftgate	Yes
Stock Number	684808
MLS Number	14393278
Category	Refrigerated Trucks
Last Updated	7/14/2026
Location	Farmingdale, NY, US
Sold By	Ryder

2021 Isuzu NPR EFI Box Truck - 401HP, 6 Speed Automatic, Roll up Door

Recently Updated

$43,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 75,052 miles, 401 HP GMC 6.6L V8 engine, 6-speed automatic GMC transmission, single rear axle with spring suspension, 150" wheelbase, 30-gallon...

Condition	Used
Usage	76,153 Miles
Duty Class	Light Duty Box Truck
Horse Power	401 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	14,500 lb 4.30 ratio
Door Type	Roll up
Stock Number	7211123
MLS Number	14452822
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Plymouth, MI, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Price Drop $35,750 USD

Used 2023 Isuzu NPR EFI box truck for sale, 120,064 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic 6L90E transmission, single rear axle, spring suspension, 30-gallon fuel...

Condition	Used
Usage	137,369 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	520457
MLS Number	14016226
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Dothan, AL, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$35,000 USD

Used 2023 Isuzu NPR EFI Box Truck for sale, 350HP GMC 6.6LV8 gasoline engine, 6-speed automatic transmission, 150-inch wheelbase, 30-gallon fuel capacity, yellow with roll-up door. Check it...

Condition	Used
Usage	143,975 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	519638
MLS Number	14016219
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Jamaica, NY, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Price Drop $37,250 USD

Used 2023 Isuzu NPR EFI box truck for sale, 127,144 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, spring suspension, roll-up door. Check it out...

Condition	Used
Usage	129,371 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	516399
MLS Number	14433853
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Pensacola, FL, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$42,750 USD

Used 2023 Isuzu NPR EFI Box Truck for sale, 108,961 miles, 350 HP GMC 6.6LV8 gasoline engine, 6-speed GMC automatic transmission, single rear axle, 30-gallon fuel capacity, roll-up door....

Condition	Used
Usage	120,825 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	505668
MLS Number	14016202
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Dothan, AL, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$43,500 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, 150" wheelbase, 30-gallon fuel capacity, white, roll-up door...

Condition	Used
Usage	101,902 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	410703
MLS Number	14432153
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Tampa, FL, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$38,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 114,065 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, roll-up door, white, light duty GVWR. Check it out!

Condition	Used
Usage	117,514 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	410682
MLS Number	13524231
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Obetz, OH, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 102,033 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, roll-up door, spring suspension, light duty GVWR. Check it...

Condition	Used
Usage	106,657 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487869
MLS Number	14284163
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Columbus, OH, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,000 USD

Used 2021 Isuzu NPR EFI box truck for sale, 350HP 6.6LV8 GMC gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, yellow with roll-up door. See it now.

Condition	Used
Usage	106,744 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487858
MLS Number	14347122
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	La Porte, IN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,000 USD

Used 2021 Isuzu NPR EFI box truck for sale, 85,251 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, spring suspension, roll-up door. Check it out!

Condition	Used
Usage	90,074 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487857
MLS Number	14388027
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Brooklyn Park, MN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 350 HP GMC 6.6LV8 gasoline engine, 6-speed automatic Transmission, 105,501 miles, roll-up door, 150-inch wheelbase, 30-gallon fuel capacity. Check...

Condition	Used
Usage	107,450 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487811
MLS Number	14433626
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	South Plainfield, NJ, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$34,250 USD

Used 2021 Isuzu NPR EFI Box Truck, 350HP GMC 6.6LV8 gasoline engine, 6-speed Automatic (6L90E), single rear axle, 150" wheelbase, 30-gallon fuel capacity, roll-up door. Check it out.

Condition	Used
Usage	133,194 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487785
MLS Number	14167066
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Akron, OH, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$36,500 USD

Used 2021 Isuzu NPR EFI box truck for sale, 98,692 miles, 350 HP 6.6L V8 GMC engine, 6-speed automatic transmission, single rear axle, 12'6" height, 150" wheelbase, roll-up door. Check it...

Condition	Used
Usage	110,703 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487766
MLS Number	14065700
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Lansing, MI, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Price Drop $39,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 96,313 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, spring suspension, roll-up door. See it now...

Condition	Used
Usage	103,095 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487749
MLS Number	14439685
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Akron, OH, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$38,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 95,088 miles, 350 HP 6.6L V8 gasoline engine, 6-speed automatic GMC transmission, roll-up door, single rear axle, spring suspension, 126" height....

Condition	Used
Usage	96,016 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487691
MLS Number	14455934
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Milwaukee, WI, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 108,600 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, spring suspension, 30-gallon fuel capacity....

Condition	Used
Usage	109,574 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487501
MLS Number	14466769
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Louisville, KY, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$42,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 79,911 miles, 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, white, roll-up door, 150-inch wheelbase, light duty GVWR. Check...

Condition	Used
Usage	84,475 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487444
MLS Number	14348359
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Evansville, IN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$42,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 78,382 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, white with roll-up...

Condition	Used
Usage	83,468 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487397
MLS Number	14347119
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Elkhart, IN, US
Sold By	Penske Used Trucks

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated

$41,750 USD

Used 2020 Isuzu NPR EFI Gasoline Box Truck for sale, 297 HP GMC 6.0L V8 engine, 6-speed automatic transmission by GMC, single rear axle, 103,696 miles, 150" wheelbase, roll-up door. Check it...

Condition	Used
Usage	111,580 Miles
Duty Class	Light Duty Box Truck
Horse Power	297 HP
Engine Model	GMC 6.0LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	378403
MLS Number	14081666
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	Mebane, NC, US
Sold By	Penske Used Trucks

2020 Isuzu NPR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Recently Updated

$34,250 USD

Used 2020 Isuzu NPR Box Truck for sale, 152,655 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, single rear axle, spring suspension, white, roll-up door. Come...

Condition	Used
Usage	159,252 Miles
Duty Class	Light Duty Box Truck
Horse Power	215 HP
Engine Model	Isuzu 4HK1TC
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 4.56 ratio
Door Type	Roll up
Stock Number	374135
MLS Number	14062539
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/18/2026
Location	West Sacramento, CA, US
Sold By	Penske Used Trucks