Used Isuzu NPR Trucks For Sale

Featured Item

2020 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door

$19,000 USD

Condition	Used
Usage	242,354 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.55 ratio
Door Type	Roll up
Stock Number	271871
MLS Number	14423023
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/6/2026
Location	Ashland, VA, US
Sold By	Ryder

Featured Item

2019 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$28,990 USD

Condition	Used
Usage	162,942 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.55 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	264919
MLS Number	14399766
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/6/2026
Location	Pittsburgh, PA, US
Sold By	Ryder

Featured Item

2018 Isuzu NPR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

$43,712 USD

Condition	Used
Usage	193,217 Miles
Duty Class	Medium Duty Refrigerated Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	812599
MLS Number	14398039
Category	Refrigerated Trucks
Last Updated	7/6/2026
Location	Greensboro, NC, US
Sold By	Ryder

Featured Item

2017 Isuzu NPR 18 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

$52,514 USD

Condition	Used
Usage	66,215 Miles
Duty Class	Medium Duty Refrigerated Truck
Box Length	18 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Swing
Liftgate	Yes
Stock Number	684808
MLS Number	14393278
Category	Refrigerated Trucks
Last Updated	7/6/2026
Location	Farmingdale, NY, US
Sold By	Ryder

2021 Isuzu NPR EFI Box Truck - 401HP, 6 Speed Automatic, Roll up Door

Recently Updated

$43,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 75,052 miles, 401 HP GMC 6.6L V8 engine, 6-speed automatic GMC transmission, single rear axle with spring suspension, 150" wheelbase, 30-gallon...

Condition	Used
Usage	75,581 Miles
Duty Class	Light Duty Box Truck
Horse Power	401 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	14,500 lb 4.30 ratio
Door Type	Roll up
Stock Number	7211123
MLS Number	14452822
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Plymouth, MI, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,000 USD

Used 2023 Isuzu NPR EFI box truck for sale, 120,064 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic 6L90E transmission, single rear axle, spring suspension, 30-gallon fuel...

Condition	Used
Usage	136,989 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	520457
MLS Number	14016226
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Dothan, AL, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$35,000 USD

Used 2023 Isuzu NPR EFI Box Truck for sale, 350HP GMC 6.6LV8 gasoline engine, 6-speed automatic transmission, 150-inch wheelbase, 30-gallon fuel capacity, yellow with roll-up door. Check it...

Condition	Used
Usage	141,846 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	519638
MLS Number	14016219
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Jamaica, NY, US
Sold By	Penske Used Trucks

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$40,250 USD

Used 2023 Isuzu NPR EFI box truck for sale, 127,144 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, spring suspension, roll-up door. Check it out...

Condition	Used
Usage	129,056 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	516399
MLS Number	14433853
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Pensacola, FL, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$43,500 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, 150" wheelbase, 30-gallon fuel capacity, white, roll-up door...

Condition	Used
Usage	101,776 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	410703
MLS Number	14432153
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Tampa, FL, US
Sold By	Penske Used Trucks

2022 Isuzu NPR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Price Drop $43,000 USD

Used 2022 Isuzu NPR Box Truck for sale, 70,342 miles, 215 HP Isuzu diesel engine, 6-speed Aisin automatic transmission, single rear axle, spring suspension, 30-gallon fuel capacity, roll-up...

Condition	Used
Usage	70,343 Miles
Duty Class	Light Duty Box Truck
Horse Power	215 HP
Engine Model	Isuzu 4HK1TC
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 4.56 ratio
Door Type	Roll up
Stock Number	419778
MLS Number	13630788
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Kansas City, MO, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,500 USD

Used 2021 Isuzu NPR EFI box truck for sale, 85,610 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity. See it now.

Condition	Used
Usage	85,803 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487936
MLS Number	14454622
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Lansing, MI, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 104,991 miles, 350HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, roll-up door. Check...

Condition	Used
Usage	105,459 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487881
MLS Number	14446953
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Capitol Heights, MD, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 102,033 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, roll-up door, spring suspension, light duty GVWR. Check it...

Condition	Used
Usage	106,280 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487869
MLS Number	14284163
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Columbus, OH, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,000 USD

Used 2021 Isuzu NPR EFI box truck for sale, 350HP 6.6LV8 GMC gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, yellow with roll-up door. See it now.

Condition	Used
Usage	106,054 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487858
MLS Number	14347122
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	La Porte, IN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$41,000 USD

Used 2021 Isuzu NPR EFI box truck, 350HP GMC 6.6LV8 gasoline engine, 6-speed automatic transmission, roll-up door, 100,964 miles, 150" wheelbase, single rear axle. Check it out today.

Condition	Used
Usage	101,541 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487849
MLS Number	14450384
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Tampa, FL, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 350 HP GMC 6.6LV8 gasoline engine, 6-speed automatic Transmission, 105,501 miles, roll-up door, 150-inch wheelbase, 30-gallon fuel capacity. Check...

Condition	Used
Usage	107,026 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487811
MLS Number	14433626
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	South Plainfield, NJ, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$36,750 USD

Used 2021 Isuzu NPR EFI box truck for sale, 98,692 miles, 350 HP 6.6L V8 GMC engine, 6-speed automatic transmission, single rear axle, 12'6" height, 150" wheelbase, roll-up door. Check it...

Condition	Used
Usage	110,025 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487766
MLS Number	14065700
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Lansing, MI, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$40,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 96,313 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, spring suspension, roll-up door. See it now...

Condition	Used
Usage	102,650 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487749
MLS Number	14439685
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Akron, OH, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$35,500 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 111,509 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, roll-up door, single rear axle, 150-inch wheelbase. Check it...

Condition	Used
Usage	119,051 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487719
MLS Number	14015538
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Montgomery, NY, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 108,600 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, spring suspension, 30-gallon fuel capacity....

Condition	Used
Usage	108,941 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487501
MLS Number	14466769
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Louisville, KY, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$42,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 79,911 miles, 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, white, roll-up door, 150-inch wheelbase, light duty GVWR. Check...

Condition	Used
Usage	83,590 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487444
MLS Number	14348359
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Evansville, IN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$42,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 78,382 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, white with roll-up...

Condition	Used
Usage	82,844 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487397
MLS Number	14347119
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Elkhart, IN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$40,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 98,726 miles, 350 HP 6.6L V8 gasoline engine, 6-speed automatic transmission by GMC, single rear axle, 30-gallon fuel capacity. Check it out.

Condition	Used
Usage	101,667 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487396
MLS Number	14400855
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Evansville, IN, US
Sold By	Penske Used Trucks

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,250 USD

Used 2020 Isuzu NPR EFI box truck for sale, 297 HP GMC V8 engine, 6-speed automatic transmission, gasoline fuel, single rear axle, 150" wheelbase, roll-up door, 30-gallon fuel capacity....

Condition	Used
Usage	112,632 Miles
Duty Class	Light Duty Box Truck
Horse Power	297 HP
Engine Model	GMC 6.0LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	378169
MLS Number	14159386
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	7/11/2026
Location	Lexington, KY, US
Sold By	Penske Used Trucks