Used Isuzu NPR Trucks For Sale in United States

Featured Item

2019 Isuzu NPR 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$39,732 USD

Condition	Used
Usage	58,916 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	241720
MLS Number	14388424
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/13/2026
Location	Bolingbrook, IL, US
Sold By	Ryder

Featured Item

2018 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

$35,352 USD

Condition	Used
Usage	104,929 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.55 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	810346
MLS Number	14438343
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/13/2026
Location	Bolingbrook, IL, US
Sold By	Ryder

Featured Item

2019 Isuzu NPR 16 ft Box Truck - 280HP, 6 Speed Automatic, Roll up Door, Liftgate

$37,872 USD

Condition	Used
Usage	120,936 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	280 HP
Engine Model	280/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	241714
MLS Number	14398080
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/13/2026
Location	Bolingbrook, IL, US
Sold By	Ryder

Featured Item

2018 Isuzu NPR 16 ft Refrigerated Truck - 215HP, 6 Speed Automatic, Liftgate

$46,741 USD

Condition	Used
Usage	175,907 Miles
Duty Class	Medium Duty Refrigerated Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.77 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	745051
MLS Number	14393285
Category	Refrigerated Trucks
Last Updated	8/13/2026
Location	Norwood, MA, US
Sold By	Ryder

2019 Isuzu NPR HD 16 ft Box Truck - 215HP, 6 Speed Automatic, Roll up Door, Liftgate

Recently Updated

$24,495 USD

Condition	Used
Usage	176,998 Miles
Duty Class	Medium Duty Box Truck
Box Length	16 ft.
Horse Power	215 HP
Engine Model	4HK1TC'10 215/2500
Transmission	6 Speed Automatic
Suspension	Leaf Springs
Rear Axle	Single Axle
Rear End	4.55 ratio
Door Type	Roll up
Liftgate	Yes
Stock Number	867705
MLS Number	13560935
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Pittsburgh, PA, US
Sold By	Ryder

2024 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Newly Listed

$34,000 USD

Used 2024 Isuzu NPR EFI Box Truck for sale, 169,540 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic GMC transmission, single rear axle, spring suspension, roll-up door. See it...

Condition	Used
Usage	169,540 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	14,550 lb 4.30 ratio
Door Type	Roll up
Stock Number	593111
MLS Number	14555035
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Huntington, WV, US
Sold By	Penske Used Trucks

2022 Isuzu NPR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Recently Updated

$51,500 USD

Used 2022 Isuzu NPR Box Truck for sale, 74,103 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, 150-inch wheelbase, spring suspension, single rear axle. Check...

Condition	Used
Usage	74,112 Miles
Duty Class	Light Duty Box Truck
Horse Power	215 HP
Engine Model	Isuzu 4HK1TC
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 4.56 ratio
Door Type	Roll up
Stock Number	415001
MLS Number	14498115
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Phoenix, AZ, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$34,000 USD

Used 2021 Isuzu NPR EFI box truck for sale, 122,994 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, yellow, roll-up door, 150-inch wheelbase, light-duty GVWR. Book...

Condition	Used
Usage	134,091 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487872
MLS Number	14015547
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Tallahassee, FL, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$28,750 USD

Used 2021 Isuzu NPR EFI box truck for sale, 157,201 miles, 350HP 6.6L V8 engine by GMC, 6-speed automatic transmission, single rear axle, roll-up door, gasoline, 30-gallon fuel tank. Check...

Condition	Used
Usage	160,639 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487862
MLS Number	14522880
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Norcross, GA, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$38,750 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 103,782 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, roll-up door, yellow...

Condition	Used
Usage	107,371 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487851
MLS Number	14358408
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Harahan, LA, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$36,000 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 350HP 6.6LV8 GMC gasoline engine, 6-speed automatic GMC transmission, single rear axle, spring suspension, 150-inch wheelbase. Check it out.

Condition	Used
Usage	125,611 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487828
MLS Number	14015544
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Kennesaw, GA, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$34,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 114,125 miles, 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, roll-up door, yellow...

Condition	Used
Usage	126,978 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487765
MLS Number	14015542
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Braintree, MA, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$35,500 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 111,509 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, roll-up door, single rear axle, 150-inch wheelbase. Check it...

Condition	Used
Usage	119,926 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487719
MLS Number	14015538
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Montgomery, NY, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Newly Listed

$37,000 USD

Used 2021 Isuzu NPR EFI box truck with 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic GMC transmission, single rear axle, roll-up door, 150" wheelbase, 30-gallon fuel tank. Check it...

Condition	Used
Usage	107,370 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487668
MLS Number	14554996
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Huntington, WV, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,750 USD

Used 2021 Isuzu NPR EFI box truck for sale, 350HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, 150” wheelbase, roll-up door, 109,602 miles. Don't miss...

Condition	Used
Usage	116,697 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487656
MLS Number	14364438
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Sturtevant, WI, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$40,250 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 78,554 miles, 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, roll-up door, single rear axle, 30-gallon fuel capacity. Check...

Condition	Used
Usage	78,654 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487627
MLS Number	14479844
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Milwaukee, WI, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

Contact for price

Used 2021 Isuzu NPR EFI Box Truck for sale, 95,796 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission by GMC, single rear axle, spring suspension, roll-up door. Check...

Condition	Used
Usage	100,017 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487480
MLS Number	14364437
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Linden, NJ, US
Sold By	Penske Used Trucks

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated

$41,500 USD

Used 2021 Isuzu NPR EFI Box Truck for sale, 104,484 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, white color, roll...

Condition	Used
Usage	110,120 Miles
Duty Class	Light Duty Box Truck
Horse Power	350 HP
Engine Model	GMC 6.6LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	487431
MLS Number	14383959
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	La Porte, IN, US
Sold By	Penske Used Trucks

2021 Isuzu NPR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Recently Updated

$24,750 USD

Used 2021 Isuzu NPR Box Truck for sale, 228,388 miles, 215HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, single rear axle, 150" wheelbase, 30-gallon fuel tank. Check it...

Condition	Used
Usage	231,082 Miles
Duty Class	Light Duty Box Truck
Horse Power	215 HP
Engine Model	Isuzu 4HK1TC
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 4.56 ratio
Door Type	Roll up
Stock Number	382175
MLS Number	14284124
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Essex, MD, US
Sold By	Penske Used Trucks

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,500 USD

Used 2020 Isuzu NPR EFI Box Truck, 297HP GMC 6.0L V8 gasoline engine, 6-speed automatic transmission, 150" wheelbase, single rear axle, roll-up door, spring suspension, 30-gallon fuel...

Condition	Used
Usage	126,343 Miles
Duty Class	Light Duty Box Truck
Horse Power	297 HP
Engine Model	GMC 6.0LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	378386
MLS Number	14014567
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	West Sacramento, CA, US
Sold By	Penske Used Trucks

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated

$39,500 USD

Used 2020 Isuzu NPR EFI box truck for sale, 297 HP GMC V8 engine, 6-speed automatic transmission, gasoline fuel, single rear axle, 150" wheelbase, roll-up door, 30-gallon fuel capacity....

Condition	Used
Usage	114,522 Miles
Duty Class	Light Duty Box Truck
Horse Power	297 HP
Engine Model	GMC 6.0LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	378169
MLS Number	14159386
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Lexington, KY, US
Sold By	Penske Used Trucks

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated

$37,500 USD

Used 2020 Isuzu NPR EFI Box Truck for sale, 121,897 miles, 297 HP GMC 6.0L V8 gasoline engine, 6-speed automatic transmission, single rear axle, roll-up door, white, 150-inch wheelbase....

Condition	Used
Usage	127,140 Miles
Duty Class	Light Duty Box Truck
Horse Power	297 HP
Engine Model	GMC 6.0LV8
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 5.37 ratio
Door Type	Roll up
Stock Number	378121
MLS Number	14476449
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	Duluth, GA, US
Sold By	Penske Used Trucks

2020 Isuzu NPR Box Truck - 215HP, 6 Speed Automatic, Roll up Door

Recently Updated

$34,000 USD

Used 2020 Isuzu NPR Box Truck for sale, 152,655 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, single rear axle, spring suspension, white, roll-up door. Come...

Condition	Used
Usage	160,428 Miles
Duty Class	Light Duty Box Truck
Horse Power	215 HP
Engine Model	Isuzu 4HK1TC
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 4.56 ratio
Door Type	Roll up
Stock Number	374135
MLS Number	14062539
Category	Delivery / Moving / Straight / Box Trucks
Last Updated	8/20/2026
Location	San Diego, CA, US
Sold By	Penske Used Trucks

2020 Isuzu NPR Flatbed Truck - 215HP, 6 Speed Automatic

Recently Updated

$40,250 USD

Used 2020 Isuzu NPR Flatbed Truck for sale, 97,495 miles, 215 HP Isuzu 4HK1TC diesel engine, 6-speed Aisin automatic transmission, 150-inch wheelbase, single rear axle, 30-gallon fuel tank....

Condition	Used
Usage	99,607 Miles
Duty Class	Light Duty Flatbed Truck
Horse Power	215 HP
Engine Model	Isuzu 4HK1TC
Transmission	6 Speed Automatic
Suspension	Spring
Rear Axle	Single Axle
Rear End	11,020 lb 4.56 ratio
Stock Number	373662
MLS Number	14387806
Category	Flatbed Trucks
Last Updated	8/20/2026
Location	Memphis, TN, US
Sold By	Penske Used Trucks