Used Isuzu Trucks with GMC Engines For Sale

Your Current Search
Industry
Trucks
Manufacturer
Isuzu
Engine Manufacturer
GMC
Condition
Used
Click the to remove the filter.
Narrow Your Search
Keyword Search
Search within the selected criteria
Equipment Type
Trucks (191)
Make
Isuzu (191)
Model
Select a category to view available models.
Condition
Used (191)
Model Year
-
GVWR Category
Rear Axle
Single (190)
Transmission Type
Transmission Speed
Drive Train
4x2 (1)
Suspension Type
Spring (184)
Cab Style
Regular Cab (2)
Fuel Type
Mileage
-
Horsepower
-
Price
-
Country
United States (191)
State / Region
Select a state below and click Refine Results.





























Market Type
For Sale (191)

Showing 51 - 75 of 191 Listings

51 - 75 of 191 listings
51 - 75 of 191 listings
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2023 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated
$41,000 USD
Used 2023 Isuzu NPR EFI box truck for sale, 115,878 miles, 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, single rear axle, roll-up door, 150-inch wheelbase. Check it...
ConditionUsed
Usage119,284 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number511865
MLS Number14016210
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/24/2026
Location
Atlanta, GA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated
$40,250 USD
Used 2021 Isuzu NPR EFI box truck for sale, 116,879 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, light duty GVWR. Check it out today!
ConditionUsed
Usage118,800 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number410679
MLS Number14015610
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/27/2026
Location
Orlando, FL, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated
$36,250 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 350HP GMC 6.6LV8 gas engine, 6-speed GMC automatic transmission, single rear axle, 150" wheelbase, roll-up door. Check it out today.
ConditionUsed
Usage114,447 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487792
MLS Number13905672
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/21/2026
Location
Pensacola, FL, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Newly Listed
$35,750 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 118,376 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, roll-up door, 30-gallon fuel capacity. See...
ConditionUsed
Usage118,640 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487666
MLS Number14102113
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/27/2026
Location
Virginia Beach, VA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated
$43,000 USD
Used 2021 Isuzu NPR EFI box truck for sale, 73,739 miles, 350 HP 6.6L V8 GMC engine, 6-speed automatic GMC transmission, single rear axle, roll-up door. Check it out today.
ConditionUsed
Usage79,938 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487559
MLS Number13694179
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/27/2026
Location
Harrisburg, PA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated
$39,750 USD
Used 2021 Isuzu NPR EFI Box Truck with 350HP GMC 6.6LV8 gasoline engine, 6-speed automatic GMC transmission, single rear axle, 30 gal fuel capacity, 150-inch wheelbase, white, roll-up door....
ConditionUsed
Usage105,544 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487511
MLS Number14086204
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/22/2026
Location
Norfolk, VA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Recently Updated
$38,000 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 109,830 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, white color, roll-up door, 150-inch wheelbase. Check it out.
ConditionUsed
Usage112,413 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487427
MLS Number14015520
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/27/2026
Location
Atlanta, GA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

Newly Listed
$38,500 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 84,185 miles, 350 HP 6.6L V8 engine by GMC, 6-speed automatic transmission, single rear axle, 30-gallon fuel tank, roll-up door. Check it out...
ConditionUsed
Usage84,341 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487404
MLS Number14102112
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/24/2026
Location
Albany, NY, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated
$36,000 USD
Used 2020 Isuzu NPR EFI Box Truck for sale, 107,923 miles, 297 HP 6.0L V8 GMC gas engine, 6-speed automatic transmission, 150" wheelbase, 30-gallon fuel capacity, roll-up door. Check it out!
ConditionUsed
Usage109,781 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC 6.0LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number378488
MLS Number13899457
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/27/2026
Location
Norton, MA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated
$38,500 USD
Used 2020 Isuzu NPR EFI Box Truck for sale, 95,133 miles, 297 HP 6.0L V8 gas engine by GMC, 6-speed automatic transmission, single rear axle with spring suspension, roll-up door. Check it...
ConditionUsed
Usage102,585 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC 6.0LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number378450
MLS Number13870169
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/24/2026
Location
Homewood, AL, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

2019 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

Recently Updated
$37,000 USD
Used 2019 Isuzu NPR EFI Gasoline Box Truck for sale, 297 HP GMC engine, 6-speed automatic transmission, single rear axle, 109,191 miles, 138-inch height, roll-up door, light duty. Check it...
ConditionUsed
Usage109,191 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC GMPTV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number343526
MLS Number14085582
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/21/2026
Location
Atlanta, GA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic

2019 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic

$35,750 USD
Used 2019 Isuzu NPR EFI box truck for sale, 297 HP GMC 6.0L V8 gasoline engine, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity, white color. Check it out.
ConditionUsed
Usage88,903 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC 6.0LV8
Transmission6 Speed Automatic
Rear AxleSingle Axle
Stock Number11926
MLS Number14100152
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/22/2026
Location
Kalamazoo, MI, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic

2019 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic

$33,500 USD
Used 2019 Isuzu NPR EFI Box Truck for sale, 91,887 miles, 297 HP 6.0L V8 GMC engine, 6-speed automatic transmission, single rear axle rated 11,200 lbs, 150" wheelbase, 30-gallon fuel...
ConditionUsed
Usage91,887 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC 6.0LV8
Transmission6 Speed Automatic
Rear AxleSingle Axle
Rear End11,200 lb
Stock Number11921
MLS Number14100151
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/21/2026
Location
Warren, MI, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$48,000 USD
Used 2021 Isuzu NPR EFI box truck for sale, 36,771 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, 30-gallon fuel capacity. Check it out today...
ConditionUsed
Usage36,817 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number410693
MLS Number14099948
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/23/2026
Location
Prince George, VA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$38,250 USD
Used 2021 Isuzu NPR EFI box truck for sale, 115,445 miles, 350 HP 6.6L V8 gasoline engine by GMC, 6-speed automatic transmission, single rear axle, roll-up door, 126-inch height. Check it...
ConditionUsed
Usage117,994 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487964
MLS Number14069744
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/25/2026
Location
Blountville, TN, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$36,250 USD
Used 2021 Isuzu NPR EFI box truck for sale, 350 HP GMC 6.6L V8 engine, 6-speed automatic GMC transmission, single rear axle, 119,973 miles, 150-inch wheelbase, roll-up door. Check it out.
ConditionUsed
Usage122,241 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487821
MLS Number13791587
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/20/2026
Location
Las Vegas, NV, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$36,000 USD
Used 2021 Isuzu NPR EFI box truck for sale, 98,692 miles, 350 HP 6.6L V8 GMC engine, 6-speed automatic transmission, single rear axle, 12'6" height, 150" wheelbase, roll-up door. Check it...
ConditionUsed
Usage100,578 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487766
MLS Number14065700
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/24/2026
Location
Lansing, MI, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$36,000 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 113,470 miles, 350 HP 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, roll-up door, yellow color. Check it out.
ConditionUsed
Usage117,017 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487714
MLS Number14021285
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/24/2026
Location
Dothan, AL, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$39,000 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic GMC transmission, 150" wheelbase, single rear axle, 30-gallon fuel capacity, white color,...
ConditionUsed
Usage113,357 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487608
MLS Number14099925
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/20/2026
Location
Greenville, SC, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$36,500 USD
Used 2021 Isuzu NPR EFI box truck for sale, 126,746 miles, 350 HP GMC 6.6L V8 gasoline engine, 6-speed automatic transmission, single rear axle, spring suspension, 30-gallon fuel capacity....
ConditionUsed
Usage126,746 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487380
MLS Number14099921
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/20/2026
Location
Moberly, MO, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

2020 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

$39,750 USD
Used 2020 Isuzu NPR EFI Box Truck for sale, 297HP GMC 6.0L V8 gasoline engine, 6-speed automatic transmission, 150" wheelbase, single rear axle, roll-up door, 30-gallon fuel capacity. Check...
ConditionUsed
Usage107,067 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC 6.0LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number378128
MLS Number14021172
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/22/2026
Location
Norcross, GA, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$35,500 USD
Used 2021 Isuzu NPR EFI box truck for sale, 103,896 miles, 350 HP 6.6L V8 GMC gasoline engine, 6-speed automatic transmission, 150” wheelbase, roll-up door, yellow color. Check it out.
ConditionUsed
Usage106,181 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487806
MLS Number13899795
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/17/2026
Location
North Bergen, NJ, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$39,250 USD
Used 2021 Isuzu NPR EFI box truck with 350HP gasoline GMC 6.6LV8 engine, 6-speed automatic GMC transmission, 150" wheelbase, single rear axle, spring suspension, roll-up door, 75,556 miles....
ConditionUsed
Usage80,212 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487642
MLS Number13865327
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/18/2026
Location
Mebane, NC, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 350HP, 6 Speed Automatic, Roll up Door

$31,000 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 127,289 miles, 350 HP 6.6L V8 gas engine by GMC, 6-speed automatic transmission, single rear axle, roll-up door, 30-gallon fuel capacity. Check it...
ConditionUsed
Usage132,621 Miles
Duty ClassLight Duty Box Truck
Horse Power350 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number487392
MLS Number13868365
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/21/2026
Location
Liverpool, NY, US
Sold By
Penske Used Trucks
Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

2021 Isuzu NPR EFI Box Truck - 297HP, 6 Speed Automatic, Roll up Door

$42,750 USD
Used 2021 Isuzu NPR EFI Box Truck for sale, 80,558 miles, 297 HP 6.6L V8 GMC gasoline engine, 6-speed automatic GMC transmission, 150-inch wheelbase, roll-up door, light-duty GVWR. Check it...
ConditionUsed
Usage80,558 Miles
Duty ClassLight Duty Box Truck
Horse Power297 HP
Engine ModelGMC 6.6LV8
Transmission6 Speed Automatic
SuspensionSpring
Rear AxleSingle Axle
Rear End11,020 lb 5.37 ratio
Door TypeRoll up
Stock Number374772
MLS Number14096369
CategoryDelivery / Moving / Straight / Box Trucks
Last Updated1/17/2026
Location
Akron, OH, US
Sold By
Penske Used Trucks
Did you find what you were looking for? Yes No